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Dr. Mirabile and his team of Nurse Practitioners combine the latest medical research, over 30 years of clinical experience and training to provide comprehensive womenʼs health care. Dr. Mirabile offers exceptional women’s care as well as minimally invasive procedures for gynecological treatment. We believe strongly in the physician-patient relationship and work with you in making the best decisions for your womenʼs health. We take time with every patient and try to treat each person the way we would want to be treated, or the way we wish for our families to be treated. 

Hormone replacement therapy is not a one-size fits all. Our focus is not simply on prescribing, but on combining the appropriate dosage and delivery method to balance a patientʼs hormones. Each person is different, and their needs change over time. This is why itʼs important to have an individualized program designed for each patient. Dr. Mirabile and our team of highly experienced Nurse Practitioners treat both men and women with highly effective, customized compounded prescriptions. We treat women with troches, pills, injections and creams and both men and women with SottoPelle®.

At Mirabile M.D. MedCosmetic, we offer the latest in non-surgical treatments including Botox®, Dysport®, Daxxify®, dermal fillers, laser hair removal, fractional laser treatments, radio frequency treatments, body contouring, facials, chemical peels, feminine wellness and more. Since 1999, we have offered our medical spa patients expert treatments under the supervision of founder and on-site medical director, James Mirabile, M.D. As a top Kansas City med spa, we use the most advanced devices and products to treat unwanted hair, fine lines and wrinkles, sun damage and age spots, acne and acne scarring, rosacea, veins, unwanted tattoos, sagging skin and much more. 

Our medical weight loss team, led by owner and on-site physician, James Mirabile M.D., will customize a weight loss program for your specific goals, lifestyle and health history. The advancements in wellness and obesity medicine are exciting and give us a variety of tools to help you achieve your goals and improve your health. The Mirabile M.D. weight loss and personalized wellness programs include versatile nutrition plans as well as prescription medications including appetite suppressants and weight loss injections, Semaglutide and Tirzepatide. In addition, we offer a full vitamin injection menu and high-quality supplements to help support your weight loss efforts.

July Specials

Enjoy special offers on medical spa products and services, including our exclusive Hydrafacial Deluxe!


“This place — it’s the real deal. I first visited Dr. Mirabile when I was wrapping up chemotherapy treatments. I needed to get my hormone treatments started and Dr. Mirabile personally took care of me. He was very caring and despite my then-current medical history – he listened – understood what I was relaying and very carefully prescribed what I needed. He and the staff are caring and treat me very well. I highly recommend him and his team.”

–Kim of Kansas City

“I tried so many diets and exercise programs,  but could never lose more than a few pounds. After 9 months on Semaglutide, I lost 48 pounds and 23 inches! My body fat decreased by 8.5% and my BMI dropped from 31.5 to 24.2. I have so much energy and have never felt better. The nutritionists at Mirabile M.D.  guided me every step of the way with a personalized nutrition program. Thank you Mirabile M.D. team! “

–Lisa of Gladstone

“I’ve had a variety of services  from general health to gynecology to medical spa services. Dr. Mirabile genuinely cares about his patient’s wellbeing and his follow-up is like none other! Tama and Sophia have given me extra tender care with cosmetic and skin care services and they exceeded all expectations! I highly recommend this practice and refer relatives and friends all the time! Thank you for all you do Mirabile M.D.! “

–Ashley of Overland Park 

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Why Us?

Welcome to Mirabile M.D. Beauty, Health and Wellness, is your one-stop shop for total wellness. James Mirabile, M.D. founded this center on the realization that patients’ issues are often interrelated. By combining gynecology, hormone therapy, weight loss, and medical aesthetics into one convenient center, we can offer patients a synergistic approach to wellness. Dr. Mirabile and his team understand that fibroids, depression, hormone deficiency, or migraines can be as debilitating as weight gain, acne, unsightly hair growth, rosacea, or wrinkles. Our state-of-the-art facility, located at I-435 and Roe in Overland Park, KS serves the entire Kansas City metropolitan area. We look forward to meeting you soon.

Gynecology and Hormone Therapy Patients

Mission Statement

We are dedicated to providing our patients with high-quality services, compassionate care, leading-edge technology, and personalized treatments. Our patient-centric approach to beauty, health, and wellness empowers men and women to live healthier and happier lifestyles.